Research Areas
| THEMES | AREAS | RESEARCH | ||
| Cell biology ageing | Gene coding and chromosome damage | Research on intracellular signalling, DNA and RNA damage, telomere maintenance and mutagenesis | ||
| Epigenetics | Research on epigenetic modifications that impact on gene transcription (link genes, behaviour and life styles) | |||
| Proteostasis | Research on protein dynamics, proteasome function and protein aggregates | |||
| Cell metabolism and nutrient sensing | Research on cellular basis of metabolic diseases, bioenergetics and oxidative stress | |||
| Inflammation and intercellular communication | Research on immune system response, inflammation and intercellular communication mechanisms | |||
| Senescense and stem cells exhaustion | Research on cell death, cell senescence and dynamics of stem cell niches | |||
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Degeneration of biological systems in ageing |
Metabolic diseases - diabetes | Research on degeneration of biological systems in metabolic diseases, including diabetes | ||
| Sarcopenia and musculoskeletal diseases | Research on degeneration of musculoskeletal components and sarcopenia | |||
| Frailty syndrome | Research on frailty addressing key components of frailty syndrome: physical, cognitive, environment | |||
| Chronic respiratory disease | Research on chronic respiratory diseases and impact into health outcomes and quality of life | |||
| Cardiovascular diseases | Research on research on heart, vessels and blood functions | |||
| Prevention, treatment and repair in ageing | Epidemiology | Research on population cohorts, demographic and life style measurements, sampling and biobanking | ||
| Healthy life styles | Research on health outcomes and lifestyles, including interventions related with healthy nutritrion and physical activity | |||
| Cancer | Research on target interventions in brain cancers | |||
| Drug targets | Research on identification of innovative drug targets and drug delivery systems | |||
| Gene therapy | Research on development of innovative formulations for gene therapy of neurodegenerative and rare diseases associated with fast ageing and cancer | |||
| Stem cell-based regenerative medicine | Research on lifestyle interventions and dynamics of stem cell niches and stem-cell based advanced therapies |